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Priligy is one of the drugs of the class of non-selective serotonin reuptake inhibitors. Priligy improves the control of ejaculation and significantly extends sexual intercourse due to its impact over the receptors in a man’s brain.

  • Priligy is available in the form of film-coated tablets;
  • Priligy tablets contain 30 mg or 60 mg of Dapoxetine hydrochloride.

Prescribing Information

Priligy is prescribedto men aged 18 to 64 years for the treatment of premature ejaculation (PE). Priligy tablets should be taken only when a man is diagnosed with PE, including if:

  • premature ejaculation persists for more than half a year;
  • the maximum time from the onset of intercourse to ejaculation is less than two minutes.

Priligy tablets are not intended to prolong sexual intercourse in men without PE, including in adolescents under 18 years of age.


Priligy is the only drug to treat PE, which should be taken immediately before an intercourse (about 1 to 3 hours), and not on a regular basis.

Premature ejaculation treatment should begin with a minimum effective Priligydose of 30 mg. The maximum daily dose of Priligy is 60 mg. The maximum dose of Priligy should be taken only ifa single dose of 30 mg:

  • failed to prevent premature ejaculation;
  • time until ejaculation was not enough for a full sexual intercourse.

The minimum interval between two doses of Priligy is one day.


Because of the high likelihood of adverse events, Priligy is contraindicated in conjunction with such strong antiretroviral drugs, as:

Ritonavir (Norvir)

Nelfinavir (Viracept)

Atazanavir (Reyataz)

Priligy dose reduction is recommended when used concomitantly with moderate or mild CYP3A4 inhibitors, like Amprenavir (Agenerase), Verapamil (Calan), or Aprepitant (Emend).

To avoid orthostatic hypotension, it is not recommended to take Priligy in conjunction with PDE5 inhibitors, including Sildenafil (Viagra) or Avanafil (Stendra). To reduce the risk of unwanted events of Priligy, alcoholconsumption is not recommendedwhile using these tablets.

Side effects

Priligy can cause such frequent dose-depended adverse reactions, as diarrhea, nausea, insomnia, headaches, fatigue, and dizziness. Other frequent adverse reactions of Priligy are ringing in the ears, constipation, irritability, flushing or excessive sweating.

Simultaneous use with alcoholincreases the risk and/or intensity of Priligyside effects from the CNS, including fainting. If Priligy is abruptly terminated, it can cause:

  • apathy
  • sleep disorders
  • strong arousal
  • emotional lability

The risk and/or intensity of adverse events of Priligy can be reducedby adjusting the dose of this drug for the PEtreatment.


Priligy is designed exclusively for men with PE. The results of several clinical studies have proven the inexpediency of Priligy use in women.

Priligy contains lactose, and can cause a hypersensitivity reaction in the presence of lactose intolerance. For this reason, men with this digestive system disorder are not allowed to take Priligy.

Men with a history of orthostatic hypertension are advised to follow precautions when using Priligy, or to choose an alternative treatment for PE.