Description
Nexium
The drug Nexium offers real solutions for people, who suffer from acid-related diseases. The use of the drug allows to cure or control acid-dependent diseases without negative health consequences.
Prescribing Information
Nexium depresses the secretion of gastric juiceday and night. The drug is used to treat light, moderate or severe peptic diseases:
- Gastroesophageal reflux disease – usually within 28 days.
- Pathological hypersecretory disease – the drug is used as long as clinically indicated.
The drug is also indicated for pharmacological treatment, prophylaxis or prevention of stomach ulcers recurrences,caused by the use of medications (e.g., NSAID painkillers) or Helicobacter pylori bacteria.
Dosage
Nexium capsules or oral suspension should be taken once every 24 hours (usually). Oral administration of the drug before meals will reduce the risk of gastrointestinal side effects.
A single dose of Nexium depends on the nature and severity of the acid-dependent disease, the patient’s age, the function of the internal organs and other factors.
- The recommended dose for adults is 20 mg or 40 mg of Nexium per day.
- Doses for children are selected based on body weight.
Doses up to 160 mg of Nexium per day can be usedto control and treat hypersecretory disease. Doses in excess of 80 mg are better divided into two doses.
Interactions
Whenever a patient takes Nexium with any other drug or food supplement, there is a chance for an interaction between them.
Nexium can interact with drugs for the treatment of tuberculosis (Rifampicin), epilepsy (Phenytoin), infections (Voriconazole), leg pain (Cilostazol), heartburn (Cisapride), depression (Clomipramine) and others.
Nexium increases the pH of the stomach – an important factor that determines the bioavailability of any medication (for example, protease inhibitors). Therefore, patients are better to consult with a doctorbefore they proceed with coadministration of any drugs. This will allow to effectively treat acid-dependent diseases and reduce the risks of adverse reactions.
Side effects
Nexium usually reduces the secretion of gastric juice without any untoward medical occurrences. Rarely,the response to Nexium may be negative, especially when the drug is used for a long time in high doses (more than 40 mg).
Complete list of frequent adverse events of Nexium includes cramps or abdominal pain, nausea, head pain and diarrhea. In rarer cases, patients experience problems with falling asleep, increased sweating, taste disturbance, peripheral oedema, aggressiveness, dizziness or bronchospasm.
Most adverse reactions are not a cause for concern, a decrease in the daily dose or discontinuation of the treatment for acid-dependent diseases. As a rule, they wear off in a few hours after Nexium administration.
Tips
Before you begin Nexium treatment, you should read the leaflet and check out the possible side effects. This will allow you to discover them in time and take the necessary measures.
Nexium should be stored in accordance with the instructions, since moisture and high temperature (exceeding 30°C) can adversely affect the drug efficacy. Do not take Nexium if expired.