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Meridia is a medicine for the treatment of obesity, which helps to solve the problem of excess weight by suppressing appetite. Meridia promotes the normalization of eating behavior and helps people overcome the ever-occurring hunger, which makes them eat and gain weight.

Prescribing Information

Meridia will help excessively overweightpeople to lose weight. The maximum effectiveness of anti-obesity therapy is provided by a unique dual therapeutic effect of Meridia:

  • Inhibition of serotonin reuptake – helps suppress appetite and reduce the amount of food consumed as a result of rapid saturation
  • Inhibition of norepinephrine reuptake – increases thermogenesis and energy expenditure.

Thus, Meridia regulates all aspects of feeding behavior and increases the intensity of fat burning. As a result of Meridia use, body weight is normalized and the tendency to overeat disappears.

In anti-obesity therapy, Meridia tablets are used, each of which may contain 5 mg, 10 mgor 15 mg of the active ingredient Sibutramine.


The initial dose of Meridia, required for body weightreduction, is 5-10 mg per day. After a month of the anti-obesity therapy, the daily dose of Meridia can be increased to 15 mg.

In combination with isocaloric diet and moderate exercise, Meridia contributes to a pronounced weight loss. With insufficient therapeutic effect, the use of the anorectic can be extended for another 6 months. The total duration of Meridia treatment should not exceed 2 years.

The purpose of Meridia use for anti-obesity therapy:

  • Significant weight loss.
  • Normalization of eating behavior.
  • Decrease in caloric content of daily ration.
  • Development and consolidation of proper eating habits.


The interaction of Meridia with MAO inhibitors, selective serotonin reuptake inhibitors (SSRIs), and any drug that affects the uptake or release of serotonin, can cause serotonin syndrome, which is characterized by excitation, hyperthermia, autonomic disorders and myoclonia.

In addition, it is noteworthy to take into account the occurrence of undesirable effects in the interaction of Meridia with drugs that increase blood pressure. The anorectic can not be taken with drugs for the treatment of colds or allergies, such as Dextromethorphan, Ephedrine, Glucocorticoids, etc.

Because of the risk of internal bleeding, it is recommended to avoid interaction of Meridia with anticoagulants (Dicumarin, Warfarin, Neodicumarin, Pelentane, Phenylin, Syncumar and others).

Side effects

The anti-obesity therapy with Meridia can be complicated by side effects, especially if the drug is prescribed without the account being taken of contraindications to use and to people with a slight weightexcess. The main undesirable reactions of Meridia are dry mouth, dizziness, heart rhythm disturbance or insomnia.

Side effects of Meridia occur only in the first 2-3 weeks of the anti-obesity therapy. Unwanted reactions usually pass on their own, do not make up a significant cause for concern and do not require the therapywithdrawal.


For the most secure and effective anti-obesity therapy with Meridia, several recommendations must be followed.

  • To increase the efficacy of the pharmacotherapy, patient should keep a low-calorie diet plan and perform daily physical activities;
  • Since Meridia affects heart function, careful monitoring of blood pressure and heart rate are required every 2 weeks for the first 3 months of therapy, and then every 1-3 months.