Flagyl is one of the drugs, suitable for the rapid treatment of intractable bacterial and fungal infections. Flagyl solves the main task of treating infectious diseases – it stops the infectious process at the initial phase of its development and does not allow its further progression.
Flagyl is a highly active antimicrobial and antiprotozoal drug that has a broad spectrum of activity against infectious and parasitic infections. The spectrum of therapeutic indications for the use of Flagyl is unusually wide:
- Treatment of protozoal infections – rosacea, leishmaniasis, amebiasis and others;
- Treatment of anaerobic infections of the respiratory system, urinary tract, gastrointestinal tract.
The action mechanism of Flagyl lies in the inhibition of the nucleic acids synthesis that are necessary for the life of microorganisms. The violation of bacterial DNA eventually leads to their death.
In antimicrobial and antiparasitic therapy, tablets, capsules, oral suspension, rectal and vaginal (pessary) suppositories, as well as Flagyl injection, can be used.
The dosage of Flagyl depends on which dosage form was chosen for antibiotic therapy.
Maximum recommended doses of different Flagylforms:
- Injection solution: up to 2 mg per day;
- Rectal suppositories: one suppository three times a day;
- Tablets, capsules and oral suspension: up to 750 mg three times a day;
- Vaginal suppositories (pessaries): one suppository per day + up to 400 mg of oral Flagyl.
Antimicrobial and antiparasitic therapy with Flagyl can last 1 to 10 days. According to the recommendations of the attending physician, patients can switch from one dosage form of Flagyl to anotheror combine several dosage formsduring the treatment.
Flagyl can enhance the effect and increase the metabolism of indirect anticoagulants. As a result, blood coagulability is disrupted and thrombi can develop.
Flagyl can increase plasma concentrations of Busulfan, Cyclosporine and Lithium. In simultaneous use with alcohol, Flagyl strengthens the toxicological influence of ethanol on organs and systems of the body.
When all recommendations for the use of therapeutic Flagyl dosesare followed, it does not cause serious side effects. Only in prolonged use or in an overdose with Flagyl, cramps, headaches, nausea, vomiting, or sleep disturbances may occur.
To improve the efficacy of antimicrobial and antiparasitic therapy, several recommendations should be followed.
The use of Flagyl should continue until the complete eradication of infectious agents from the body;
If the infection symptoms persist, and the allowable duration of therapy is exceeded, the advisability of further Flagyl use should be assessed only by the attending physician;
To overcome the resistance of microorganisms to the action of Flagyl, doctors may recommend increasing the dosage or increasing the treatmentduration;
Before the start of therapy, it is necessary to minimize or completely eliminate the risk factors that contribute to the emergence and progression of bacterial and fungal infections (unprotected sexual intercourse, eating unwashed and poorly prepared foods, etc.).